Accordingly, the use of antidiabetic drugs that are less likely to cause hypoglycemia has increased. With the announcement of the “Kumamoto Declaration 2013,” the diabetes treatment policy has changed to one that emphasizes the prevention of hypoglycemia. Moreover, since 2010, hypoglycemia, particularly severe hypoglycemia, has become a recognized risk factor for the development of coronary heart disease (CHD). Before 2010, a high premium was placed on decreasing blood sugar levels while treating diabetes, making it difficult to avoid hypoglycemia. However, since 2012 when the JJ risk engine was developed, diabetes treatment policies have changed significantly. The algorithm of this risk engine uses the multi-state Cox regression model. ![]() The JJ Risk Engine accurately predicts macro- and micro-vascular complications and provides useful information for risk classification and health economic simulations. This risk engine was developed using Japanese patient data therefore, it is expected that its prediction accuracy will be higher for Japanese subjects than for Western subjects. The Japan Diabetes Complications Study (JDCS)/the Japanese Elderly Diabetes Intervention Trial (J-EDIT) risk engine (JJ risk engine) was developed in Japan in 2012. ![]() ![]() The Creative Commons Public Domain Dedication waiver ( ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.Ĭurrently, a risk engine that calculates the probability of CHD in type 2 diabetes patients is a useful prediction method. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.
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